Is the relationship among outcome variables shown in randomized trials?
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چکیده
منابع مشابه
Is the relationship among outcome variables shown in randomized trials?
BACKGROUND Randomized controlled trials (RCTs) often have more than one primary outcome and frequently have secondary and harm outcomes. Comparison of outcomes between study arms is the primary focus of RCTs, but there are times when the relation between outcomes is important, such as determining whether an intermediate outcome and a clinical outcome have a strong association. We sought to dete...
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نابس طلاک بازطضا اب یرادییش یتخایشازف یاَدزبَار ی ٍطبار یسرزب شَیضپ هیا فدَ ٌدافتسا هتفزگ زظو رد اب تیسیج .تسا یوازیا ناسًمآ نابس نایمرد یرادییش کردی ٍجراخ زمو ی زکذم ی ثوًم دازفا رد یرادییش یتخایشازف یاَدزبَار نآ ٍجراخ نابس طلاک بازطضا ی ٌ .تسا ٌدش عقای یسرزب درًم اَ 11 ٌاگشواد ی داسآ ٌاگشواد رد لیصحت ٍب لًغشم یًجشواد ناگدییک تکزش .دودزک تکزش شَیضپ هیا رد نامزک زیَاب دیُش مراُچ ی مًس لاس نایًجشواد ٍمجزت یاَ ٍتشر رد ...
15 صفحه اولLeveraging prognostic baseline variables to gain precision in randomized trials.
We focus on estimating the average treatment effect in a randomized trial. If baseline variables are correlated with the outcome, then appropriately adjusting for these variables can improve precision. An example is the analysis of covariance (ANCOVA) estimator, which applies when the outcome is continuous, the quantity of interest is the difference in mean outcomes comparing treatment versus c...
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ژورنال
عنوان ژورنال: Trials
سال: 2015
ISSN: 1745-6215
DOI: 10.1186/s13063-015-0584-6